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With age, however, Notch activation becomes lacking due to diminished Delta expression in myofibres and in satellite cells.
Notably, we found that insufficient activation of Notch in old human satellite cells results from diminished MAPK signalling, which explains why Notch becomes lacking in old muscles, and establishes that canonical cross-talk between Notch and MAPK is to some degree conserved between invertebrate organogenesis and human muscle regeneration (Fig 5).
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That's not to say Become lacks clever algorithms of its own.
By 5 dpf, chondrocytes in wild-types had become hypertrophic, lacking dense rough ER (Fig. 2I,J).
Depression can cause children to become inattentive, lack an attention space, and feel nervous.
Its prose becomes more genteel, lacking the euphemisms which had helped make it so popular.
As I watched the film, I sensed that the drama was losing energy; it turned out that the characters were losing energy, that the lack of money became a lack of energy.
They had become boring and lacking in credibility.
Too easily, our lessons can become dull narratives, lacking intrigue and drama.
Maybe they just didn't think that the Republican Party had become quite so lacking in leadership.
Directivities of other important noise types are discussed as well; their directivities become understood, although lacking of relevant directivity data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com