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One of the issues that arises with these large-scale datasets, however, is that it becomes harder to interpret the data and identify key players.
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Since tissue specimens contain various types of cells, where the expressions of target proteins differ, protein assay results become hard to interpret and may even be misleading.
First, many panel selection strategies become harder to execute or interpret as reference data are sampled from more populations.
These panel selection strategies become harder to apply and interpret as sequencing efforts like the 1000 Genomes Project produce larger and more diverse reference sets, which led us to develop an alternative framework.
He became harder to contain.
Civilian casualties have become harder to ignore.
Third, golf has become harder to play.
Tickets have become harder to find.
New challenges became harder to find.
Hard decisions can become harder to make.
It became harder to demolish buildings of historic interest.
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