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However, it cannot be excluded that the cost of tolerance becomes evident under experimental conditions that are closer to those found in natural environments.
While in the MEF cell model the requirement of HSP70 only becomes evident under proteotoxic stress, in fibroblasts from a CMT1A patient the expression of HSP70 is beneficial in preventing the aggregation of PMP22 and alleviating proteasome impairment.
Since the proliferative effects of PGE2 were obtained in the absence of serum, it was important to determine whether or not the increased cell count reflected a bona fide mitogenic effect of PGE2 or, alternatively, a pro-survival effect that becomes evident under situations of cellular stress, such as conceivably induced by serum withdrawal.
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Moreover, we demonstrate that assessing the symmetries as either desirable or undesirable, as introduced by these authors, brings in inconsistencies, which become evident under the permutation-based interpretation.
The importance of regional wind characteristics became evident under the influence of exceptionally strong, persistent, and dry mountain winds resulting in steeper aero-dynamic gradients throughout the measured profile.
This became evident under conditions of LipA hyperproduction, indicating that an overflow mechanism exists to re-direct LipA from the normally used Sec-dependent export route into the Tat-dependent route.
Relatively little difference was observed between genotypes under control conditions, but differences became evident under stress.
A potentially greater benefit of combination therapy might become evident under a different therapeutic regimen and/or only in long-term studies.
Furthermore, the optimal α becomes smaller when ω becomes larger under negative selection, and the effects of various substitution rates across sites become evident under negative selection, emphasizing the importance of our method in the calculation under negative selection.
The differentiation in human health shocks across groups becomes evident when the pastoral system is under stress in a drought, but is not differentiated when the system is in a recovery phase.
If we assume that the position of the sub-Rouse relaxation peak is the same in the dielectric and mechanical spectra, it becomes evident that it must be hidden under the high-frequency side of the Rouse peak and the low-frequency side of the segmental peak.
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CEO of Professional Science Editing for Scientists @ prosciediting.com