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Previous data from a human model of RA had suggested a role for TLR8 in the production of TNF [ 14]; however, extrapolating this finding across species becomes difficult when considering the role of TLR8.
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At the same time, however, we would like to stress the fact that if this might be possible for quiet periods, it would become difficult when considering disturbed conditions, for which the calculation of monthly median values does not make sense.
This study shows that ethical dilemma also becomes difficult when a suspicious fetal malformation is detected.
However, interpretation becomes difficult when different species compete for sorption sites in the soil/solution system.
The keyword search becomes difficult when data are encrypted.
However, this scenario becomes difficult when multiple nodes are present or when the nodes are mobile.
Allocation becomes difficult when you have a challenge of mobilizing and extremely less resources.
Second, evaluating the efficiency of focused factories becomes difficult when there is so much diversity.
However, parameter estimation becomes slightly difficult when considering regulatory relationships.
In addition, although assessing the combined action of co-acting chemicals may be practically possible when they have the same basic mechanism of action (e.g., act on the same molecular target), the problem becomes much more difficult when considering chemicals that impact the same biological system but act through different mechanisms.
I think this would be difficult when considering disable people who are also lower-income.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com