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However, it becomes difficult to select the best primers since they do not provide information regarding the specificity of the oligonucleotides or patterns [131] [134].
Applying any optimization technique (e.g., SVM) prior to applying a feature selection method can result in the "curse of dimensionality" (e.g., a large number of features where it becomes difficult to select the representative features that are the basis for any base classification algorithm).
Similar(58)
Unfortunately, with the proliferation of systematic reviews on the same topic, it becomes difficult to make informed decisions regarding the effects of various interventions on selected outcomes.
It becomes difficult to maintain faith.
It becomes difficult to study old geomagnetic events.
However, it becomes difficult to see the patterns described above.
It becomes difficult to move.
My sense of taste changes, it becomes difficult to eat.
TB like HIV/AIDS becomes difficult to discuss in public.
Furthermore, when PCRs are multiplexed, it becomes difficult to check successful amplification per fragment, the chance of obtaining artifacts increases and equimolar loading before sequencing becomes very difficult.
Wind counterclockwise only until it becomes difficult to wind.
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