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With potentially hundreds of biologically active miRNAs interacting in this manner within neoplastic cells, it becomes difficult to elucidate the effects of a single, isolated, dysregulated miRNA on a disease state without fully appreciating the role of the miRNA within the entire transcriptome.
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It becomes difficult to maintain faith.
It becomes difficult to study old geomagnetic events.
However, it becomes difficult to see the patterns described above.
It becomes difficult to move.
My sense of taste changes, it becomes difficult to eat.
TB like HIV/AIDS becomes difficult to discuss in public.
Wind counterclockwise only until it becomes difficult to wind.
It became difficult to move.
Later, that sense of equality became difficult to maintain.
It became difficult to conduct business in a civil manner".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com