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Under such circumstances, establishing the diagnosis of PKDL and differentiating it from leprosy by traditional methods becomes difficult particularly for macular/papular cases and real time PCR assay provides a reliable alternative, being faster than routine PCR.
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Her head movements became difficult, particularly flexion, and this was accompanied by pain, more marked in the occipital and suboccipital regions.
The "Communication" subscale has no significant correlation with any subscale of PedsQL Generic Core Scale on both child self report and parent proxy report; the reason might be that when the children are not quite ignorant about their actual physical condition then it becomes difficult to communicate their feelings particularly about their health.
In this environment sex and relationships become difficult and, particularly if relations sour, hugely disruptive for the wider team.
The process described above becomes difficult to operate if the grade of concentrate falls and particularly if the lead content rises above 3 percent.
Particularly, if they are of the same order of magnitude as the recombination rate, it becomes difficult to disentangle the origin of events.
Sometimes I have pains all over the body particularly my arms, sometimes I go to bed and cannot sleep, sometimes too I sleep and waking up becomes difficult.
Gambling becomes difficult.
It becomes difficult.
Comparison shopping becomes difficult.
Thus, prediction becomes difficult.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com