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Gradually the character becomes deranged.
Too much of this, and it's the mind that becomes deranged.
When it becomes deranged, as during infections, heat is conserved unnecessarily and the temperature can exceed the normal range (see fever).
Longing to be adopted, she approaches one adult role model after another until she eventually becomes deranged by her father's repeated abuse.
After TACE, tumor microenvironment becomes deranged with increased hypoxia, leading to upregulation of hypoxia inducible factor-1 α, which in turn upregulates VEGF and PDGFR and increases tumor angiogenesis [ 42, 43], that may have adverse protumor consequences [ 44, 45].
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That's the only Trump Syndrome we ought to worry about, and it can become deranged.
While cordial at first, the man soon became "deranged," she said.
His wife who has become deranged, seeing the knife as a symbol of her husband, stabs the landlord.
"She became deranged with the loss of her beauty and how the disease had informed her strange and slightly harrowing work.
The most quiet and reserved people may become deranged loudmouths when they sit behind the keyboard, staying up until dawn and conducting angry debates on discussion boards with total strangers.
Eric knows that to charge the most secretive agency of American government with murder is to incur the suspicion that you have become deranged by anger, grief, paranoia, greed or a combination of all four.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com