Sentence examples for becomes clinically significant from inspiring English sources

To date, no clinically relevant biochemical markers have been available to indicate when IAH/ACS becomes clinically significant and thereby begins to affect end-organ perfusion.

As weights increase disproportionately relative to heights, inter-formula variability for BSA calculation becomes clinically significant.

The level at which lactate becomes clinically significant may be disputed.

A consideration is that the level at which non-adherence becomes clinically significant varies between medications.

However, in the face of the low testosterone levels seen in patients with diabetes, this polymorphism becomes clinically significant.

Clinical trials are warranted to determine whether uric acid lowering drugs can halt renal function decline before it becomes clinically significant.

There is considerable optimism that these compounds, a selection of which are here reviewed, will become clinically significant drugs.

Although patients with subclinical status may be asymptomatic, the condition can become clinically significant through the worsening of thromboembolic lesions by a natural course or surgical events such as TKA.

Using the results from the full main-effects model, we would need to use a 45-point increase in deprivation for it to become clinically significant, and a 5-year increase in age for it to become not clinically significant.

The impact of the structure-modifying effect of CS on disease symptoms may also become clinically significant only after an extended period of treatment.

This increase is largely due to a rising incidence in papillary thyroid cancer, which is associated with an overdiagnosis of small tumors that may never become clinically significant.