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Upon the inactivation of SAC, or reduction in AurkB activity, APC/C becomes active and ubiquitinates securin which leads to its degradation (Hagting et al., 2002).
At the end of mitosis, a Ras-like GTPase cascade known as the mitotic exit network (MEN) becomes active and triggers the full activation of Cdc14 and exit from mitosis (reviewed in Stegmeier and Amon 2004).
Gero Miesenböck, a physiology professor at the University of Oxford describes the technique as using "two flavors of light-responsive proteins: sensors that light up when a neuron becomes active and actuators that absorb light and turn activity on or off".
When cells reach a certain length, Pom1 gradient cannot inhibit Cdr2 kinase activity in the nodes, then Cdk1 kinase becomes active and cells enter mitosis.
Subsequently, the phosphoryl group is transferred to an aspartate residue of the cognate response regulator, which then becomes active and mediates a specific response, usually by activating and/or repressing a set of target genes.
In response to DNA damage, oncogenic activation, hypoxia or other forms of stress, p53 becomes active and triggers multiple specific events, ideally suited to cope with different stress situations.
Similar(6)
It is, however, still unclear when the KIF14/NabKin motors become active and how the motor activity is regulated.
But the germs can suddenly become active and multiply, and the patient then develops TB.
If the body's immune system weakens, tuberculosis can become active and cause disease.
"You do have to become active and do some things you don't do.
My view is you become active and stand up to the banks".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com