Sentence examples for becomes activated by binding from inspiring English sources
Inflammasome is a molecular platform for activation of caspase-1, which, when intracellular signals identify danger or microbial infection, becomes activated by binding with inflammasome to cleave such precursors of inflammatory factors as pro-IL-1β and pro-IL-18 resulting in secretion of 'mature' IL-1β and IL-18, consequently promoting the inflammatory cascade [ 43].
Upon ligand binding EGFR becomes activated by dimerisation.
Once Her4 becomes activated by phosphorylation, intracellular signalling pathways are activated, leading to further dedifferentiation of tumour cells.
The C-terminal kinase domain becomes activated by ERK-mediated phosphorylation.
However, the linear form of the peptide becomes "activated" by substituting Se for S (peptide III).
The fact that E4 failed to elicit responses that are mediated via membrane ERα raises the question of whether this is due to the failure of E4 to bind to membrane ERα or the failure of membrane ERα to become activated by E4 binding, in which case E4 would be expected to have antagonist activity on this signaling pathway.
All known RTKs become activated by the selective binding of dimeric ligands to their extracellular domains, resulting in their dimerization and autophosphorylation [1], [2].
The complement system can become activated by any of three pathways: the classical pathway relies on C1q binding, which enables the protease zymogen C1r to auto-activate and subsequently activate another protease zymogen C1s.
In the future it will be important to undertake binding studies and activation assays to determine whether mutation of these residues disrupts the ability of ubiquitinPhospho−Ser65 to bind to Parkin and become activated by PINK1.
Many Leb non-binding strains express silent babA gene sequences which may become activated by recombination into the babB locus forming chimeric babB/A genes [ 20].
The buffering effects of the protein-protein interaction allowed Mcm1 binding sites to acquire strengthening mutations such that sex determining genes became activated by Mcm1 alone.
