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This result together with the demonstration that similar efficiency can also be achieved for skipping human dystrophin exon 50 in the hDMD/mdx mouse clearly indicate that the hDMD/mdx mouse becomes a valuable model for testing AOs targeting human dystrophin when Vivo-PMO is used.
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The bumblebee has become a valuable model in ecological immunology [ 8].
The zebrafish has become a valuable model for the study of specific neuronal populations in live animals.
Physcomitrella patens has become a valuable model species based on its unique ability to integrate DNA into its nuclear genome by homologous recombination, thereby enabling rapid functional analyses by reverse genetics [ 48, 49].
More recently, zebrafish become also a valuable model to environmental and toxicological studies [ 13].
This becomes a valuable utility for preparedness planning and modeling.
Therefore, generating animal models to study genes or pathways directly regulated by DUX4 becomes a valuable alternative approach for understanding the disease mechanisms.
The Middle Easterner becomes a valuable asset.
Under these circumstances, GIS becomes a valuable tool (Pullar and Springer 2000).
Hence, the application of protocols becomes a valuable instrument when engaging in collaboration.
Murine collagen-induced arthritis (CIA) has become a valuable animal model for elucidating pathogenic mechanisms and evaluating therapeutic effects for rheumatoid arthritis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com