Sentence examples for becomes a substrate of from inspiring English sources

At the G1-S transition, p27Kip1 becomes a substrate of Skp2, which is an F-box protein that functions as the substrate recognition component of a SCF-type Cullin Ring Ligase complex in the nucleus [14], [15].

Acetylated BubR1 is a potent inhibitor of the APC/C Cdc20 complex, whereas unacetylated (or deacetylated) BubR1 readily becomes a substrate of APC/C-dependent proteolysis.

If this ability of the cell is reduced, calcein-AM accumulates in the cell and becomes a substrate of cellular esterases.

These results indicate that BubR1 might become a substrate of the APC/C complex when the SAC is satisfied.

While we demonstrated that α2AP(13-42)-HSA 13-42 -HSA 13-42 -HSA 13-42 -HSA competed for α2AP crosslinking to becamemall and macromolecular substrates, we cofld not demonstrate cross-linking to clots in vivo above background levels seen with recombinant HSA [ 19].

Interestingly, once the poly(A) tail reaches an oligo(A) length of 10 12 residues, the mRNA can become a substrate for decapping and for binding of the Pat1/ Lsm1–7 complex at the 3′ end (Tharun and Parker 2001; Chowdhury et al. 2007), which enhances the rate of decapping.

Any RNA, when in a complex with another oligoribonucleotide known as an external guide sequence (EGS), can become a substrate for ribonuclease P. Simulation of evolution in vitro was used to select EGSs that bind tightly to a target substrate messenger RNA and that increase the efficiency of cleavage of the target by human ribonuclease P to a level equal to that achieved with natural substrates.

In addition, the dismutation of superoxide radicals releases molecular oxygen that may become a substrate for the Aβ-dependent production of H2O2 (Fig. 8).

Music, in a sense, is becoming a substrate of games one could say.

This mutant form of huntingtin becomes a better substrate for TG (6, 16, 21, 23, 50) and has increased interaction with CaM (3, 49).

The glucose dependence of Δψm suggests that Nrf2 is affecting mitochondrial fatty acid oxidation (FAO) as, under conditions of glucose deprivation, FAO becomes a major provider of substrates for respiration and oxidative phosphorylation.