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Our results show that computational redesign of protein protein interfaces becomes a reliable method for altering protein binding affinity and specificity.
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Since the advent of modern microvascular techniques, the radial forearm free flap (RFFF) has become a reliable method for reconstruction of defects within the oral cavity.
Collectively, the data showed this approach to be effective in designing PS-conjugates with no disruption to the structural integrity and immunochemical properties of the PS, and thus has the potential to become a reliable method for glycoconjugate vaccine synthesis.
But an alternative explanation could be that fraudsters are as "intrinsically as poor writers as they are scientists," he says. . "More needs to be done to improve this technique if it is to become a reliable method," adds James Parry, chief executive of the United Kingdom's Research Integrity Office in London.
Comparison of the sequences of PCR-amplified fragments of genes encoding 16S rRNA, citrate synthase (gltA), or outer membrane protein (ompA) has become a reliable method for identifying rickettsiae in arthropods, including ticks (1 ).
The development of protocorms from germinated seeds and the subsequent induction of secondary protocorms or PLBs, from different tissues as explants has become a reliable method for breeding orchids.
Since the first transgenic mice were produced by microinjection of DNA into single cell embryos, i.e. zygotes, in 1981 [ 2], transgenesis has become a reliable and powerful method for the creation of new research tools.
Transgenesis by random integration of a transgene into the genome of a zygote has become a reliable and powerful method for the creation of new mouse strains that express exogenous genes, including human disease genes, tissue specific reporter genes or genes that allow for tissue specific recombination.
Since the combined therapy of FDP and MTP has been clinically proven to be significantly efficient in the treatment of hypertension, it became important to develop and validate a reliable method for the separation and determination of the two drugs in their commercially available formulations.
ARPC, however, cannot become a reliable and efficient communication method unless the problems, such as handoff and disconnection of mobile hosts, are solved.
Network analysis has become increasingly regarded in the health promotion literature as a reliable method for describing and assessing levels of community capacity and organizational collaboration [ 2- 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com