Sentence examples for become structured upon from inspiring English sources

These regions become structured upon binding of a ligand.

The C-terminus might become structured upon binding to its specific target.

It will be interesting to follow if these intrinsically disordered regions become structured upon binding to their RNA targets.

Using techniques such as NMR Nuclear Magnetic Resonancee), it has been revealed that the trans-activation domains are unstructured in unbound TFs and become structured upon binding to their partners [ 35].

We have tentatively assigned this region to the otherwise unaccounted for C-terminal domain of Cdc45; however, the density could also correspond to the disordered N-terminal tail of Mcm2, which may become structured upon Cdc45 binding.

Importantly, the HDX kinetics for peptides 370 377 and 370 384 (part of a loop) as well as 370 392 (loop and short helix) are significantly different between the apo and holoenzyme, indicating that Ca2 becomes structured upon calcium binding, which is consistent with our structural data.

The C-terminal domain has little structure in dilute solution, but becomes structured upon interaction with the DNA [ 45].

This sequence was fully conserved among all other Cbh1 proteins, and likely became structured upon substrate binding similarly, to what has been reported for other glycosyl hydrolases [ 48].

These interactions are mediated by the Sir3 BAH loop 3 which becomes structured upon NCP binding and strands B6 and B8.

The TAF2 IDR targeted by the tin(IV) oxochloride-derived inhibitor turned out to be a newly identified TAF2 DNA-binding domain that likely becomes structured upon DNA binding, perhaps reminiscent of basic domains in the leucine zipper family of activators (Shuman et al., 1990; Weiss et al., 1990).

Instability, indistinctness, dynamism, mobility, temporariness, recyclability and reversibility (Mehrotra 2008) are the fundamental elements upon which this spatial concept becomes structured.