The majority of these agents are designed to act as substrates for a protease that, when hydrolyzed at a given peptide bond, either relieve the quenching of a reporter, produce a fluorescent byproduct or become retained in tissues at the site of proteolysis [5], [6], [7], [8].
Before long, though, "we became retained by the company," as the independent directors asserted more control.
Addition of purified aggrecan monomer expanded the size of these coats as the proteoglycan became retained within the pericellular matrix.
As letter, it also provides a material base whereby the sign's distinction from other signs becomes retained and fixed.
CUG repeat RNA becomes retained in nuclear foci, where it sequesters nuclear proteins including transcription factor Sp1 and alternative splicing regulators MBNL1-3 [20], [20], [20].
Upon switching the transmembrane domain for a 18 leucine residues, ERGIC-53 became retained in the ER (Nufer et al. 2003).
This is similar to what happens for specific mutations in SCN5A, where the mutant channel becomes retained in the endoplasmic reticulum (ER) [ Liu et al., 2005; Baroudi et al., 2001].
We have shown that endogenous nuclear TLE proteins are not tightly bound in the nuclei of K562 cells and fractionate into the post-nuclear fraction; however, in the presence of exogenous PRH, endogenous TLE proteins become strongly retained in the nuclear fraction.
Neuronal precursors that incorporate the label and then become postmitotic retain high levels of the label, while cells that continue to divide dilute the label to undetectable levels.
In 2000 BMW sold the Land Rover segment to Ford, which had acquired the stock of Jaguar in 1989, while its Rover cars segment was spun off to a British consortium and became MG Rover Group Ltd. BMW retained the profitable Mini operations.
Spiegel, Murphy, Snapchat, and the Toyopa Group (one of Brown, Spiegel, and Murphy's original names for their organization, before their Pictaboo app became Snapchat) retained Cooley LLP to represent them.
