Most importantly, Rab5a S34N becomes redistributed from a diffuse cytoplasmic localization to either ruffle-like or vesicular-like structures.
During this transition, E-cadherin (also known as Shotgun) becomes redistributed from apical villous projections to bAJs (McGill et al., 2009).
Similarly, the focal adhesion protein paxillin can be phosphorylated by ATG1 and becomes redistributed from focal adhesions to the cytoplasm along with vinculin in mouse fibroblasts induced to undergo autophagy by nutrient deprivation [ 35].
In advanced stages of heart disease, connexin expression and intercellular coupling are diminished, and gap junction channels become redistributed.
When turbulence occurs through shear and rotation, the angular momentum can become redistributed to different latitudes through meridional flow.
During normal differentiation PcG proteins become redistributed whereby lineage-specific genes are expressed and pluripotency genes become silenced [41], [42], [43].
When either the Hps1 or Hps4 subunits of BLOC-3 were depleted using different siRNA duplexes, Rab32 was lost from these ring-like membranes and became redistributed to a diffuse or finely punctate cytoplasmic pattern closer to the nucleus.
During the course of MS, iron accumulates or becomes redistributed within various deep gray matter, cortical, or white matter structures.
The Zanzibar civil service, for example, became an almost entirely African organisation, and land was redistributed from Arabs to Africans.
In support of this, we found that the localization of a proteasome subunit (Rpt6-GFP) was redistributed from being predominantly nuclear in young cells to become increasingly associated with extra-nuclear granular structures during aging (Fig. 4D).
