Once these tumors grow to two centimeters or more, their treatment becomes problematic, with a high likelihood that they will metastasize from their typical original locations of the small intestine, appendix, rectum and lungs, on to the liver.
With 10 climatic regions, 14 soil regions and 11 distinct ecological regions, regional classification becomes problematic with differences in soils, topography, geology, rainfall, and plant and animal communities.
Comparing results between laboratories becomes problematic with such a diversity of protocols and DR research needs a single defined approach that could be used by the C. elegans community as a whole to compare with vertebrate studies.
While the signal adjusted for autofluorescence gives the larger contrast and more accurately reflects the specificity of the probe, this adjustment becomes problematic with tissues that have widely varying autofluorescence levels.
Such an approach is common when sustained-release dosage forms are tested but becomes problematic with immediate-release formulations (IR).
While this is doable and acceptable between two equal status biradari members, it becomes problematic with non- biradari members.
These findings support the observation we made from the number of wrong decisions: model selection becomes problematic with too close training and validation sets.
Share houses can become problematic though, with things like privacy, theft, violence and drug use.
But while the latter factor also applies to the cinematic versions – the desire of actors to record great stage roles is one reason that the shows have been filmed so often – the poetic speech can become problematic on screen, with the success of movie versions greatly depending on how they deal with the verse and soliloquies.
