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With the arrival of online chess it has become possible to systematically record games.
With the increasing availability of fully sequenced genomes across broad scales of phylogeny, it has become possible to systematically study the origin of new genes over time and thus revisit this question.
Splicing mechanisms in humans are relatively well known and with the genome tools available today, it has become possible to systematically identify genomic sites important in splicing, which in turn allows the identification of variants that may affect splicing.
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Therefore, with these classifications, it becomes possible to systematically describe the knowledge about the relation between superficial and structural features of problems.
Using automated reasoning (Kazakov et al., 2011), it then becomes possible to systematically identify equivalent, more specific and more general phenotypes across multiple species.
With the quick development of the whole genome sequencing and other "-omics" techniques, now it becomes possible to systematically explore the relationship between tumor tissues and cancer cell lines and identify the cell lines that most closely resemble particular tumor subtypes.
More recently, it has become possible to test hypomorphic or temperature-sensitive alleles of essential genes systematically (Ben-Aroya et al. 2008; Breslow et al. 2008; Li et al. 2011).
Recently, it has become possible to study these processes experimentally.
Furthermore, it becomes possible to construct genome-wide RNAi libraries that systematically target every individual gene in a given genome to perform high-throughput screening (HTS) of specific phenotypes of interests (Silva et al., 2008).
It also becomes possible to cheat.
MRA has become more useful as it becomes possible to visualize smaller vessels.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com