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With the recent emergence of continuous glucose monitoring (CGM) system, it has become possible to evaluate daily glucose fluctuation, including time in hyper- and hypoglycemia, in clinical practice.
As suitable data becomes available for a wider range of organisms, it will become possible to evaluate more effectively the effects of population size in this context.
Recently, it has become possible to evaluate the glomerular filtration rate (GFR) using a formula to calculate the estimated GFR (eGFR) in Japanese subjects [ 4]; although serum creatinine levels and the creatinine clearance rate have long been used for the evaluation of kidney function.
Moreover, since the dermal permeability of 5-FU can be significantly increased by pretreatment of the skin with microneedles, it may become possible to evaluate this treatment strategy for transdermal systemic delivery of 5-FU to treat invasive forms of BCC or other cancers (e.g., breast, colorectal, pancreatic and gastric cancers), against which intravenous 5-FU is currently approved.
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This way, it became possible to evaluate the efficiency of photocatalytic dye degradation in terms of CO2 conversion (photomineralization) simultaneously with classic UV-Vis (photobleaching) measurements within a small, lab-scale photocatalytic test setup.
As multiple whole genome transcriptomic studies aiming at identifying genes and pathways explaining variation in similar traits become available, it becomes possible to evaluate the repeatability of changes in transcriptomic patterns across studies.
By applying two-way clustering on the SA matrix (we used hierarchical clustering), it becomes possible to evaluate whether there are common subclasses that exist in both data sets.
Additionally, it becomes possible to evaluate how much the quantitative results change under changing application conditions.
Therefore, it becomes possible to evaluate quantitatively to which extent a substance bioaccumulates in humans using physiologically based pharmacokinetic/toxicokinetic models (PBPK or PBTK).
Thus, when IDSI-MRI is applied in the region of high AMT uptake, it becomes possible to evaluate cellularity due to tumor cell proliferation and immune cell infiltration in active tumor regions without including either necrosis or edema.
Methodological progress in biomedical ontology will be recognized when different methods generate results that can be objectively compared, such that it becomes possible to evaluate whether the methods yield better results.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com