Sentence examples for become most severe from inspiring English sources

But over the last several years, highway officials along the northern third of the highway, where traffic problems have become most severe, have realized that "rather than just building and maintaining it, we all have to start thinking about managing it as a 7-day-a-week, 24-hour operation, like a company or a factory," says John J. Baniak, executive director of the I-95 Corridor Coalition.

Clinical symptoms and abnormal radiographic and laboratory findings might become most severe in the second week of disease.

The Figure demonstrates the relationships between the time points when several clinical and laboratory parameters became most severe.

This colon length shortening became most severe in 5-day DSS-treated mice compared to drinking water mice colon (Fig. 2) with a reduction in colon length of around 30%.

Growing sauropod dinosaurs must have been tachymetabolic endotherms, but BMR may have decreased rapidly as maximum size was approached, when the heat loss problem became most severe, and a high BMR was no longer needed to sustain growth.

But beginning at P5, Nbasal of geAip1−/− testes was significantly decreased as compared with the control, and the decrease became most severe at P7. On the other hand, Ncentral value began to display significant increase at P5 for geAip1−/− testes.

Signs of moderate arthritis were observed in rats treated with a low dose of T-614 (5 mg/kg), which became most severe at day 18 (maximal clinical score = 2.5 ± 0.6; P = 0.0286, versus day 12) and improved significantly at day 20 (clinical score = 2.5 ± 1; P = 0.0286, versus vehicle).

It is at these times that my emotions become the most severe whirlwind: when she leaves me for that short time to be with you.

PARIS — What began with worries about the solvency of Greece in the face of high deficits, fake budget figures and low growth has quickly become the most severe test of the 16-nation euro zone in its 11-year history.

In China today, pollution threatens public health and has become the most severe environmental problem.

It has become the most severe leaf rust outbreak since the disease first appeared in the region three decades ago.