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They break through the tracheal passages, migrate into the digestive tract, and become localized in the large intestine, maturing and producing eggs there.
The mechanism by which Tud become localized in the pole plasm remains however unknown.
As a second mechanism of receptor organization, many GPCRs become localized in membrane microdomains, including lipid rafts and caveolae.
Together, these results suggest that upon adaptation of migratory polarity, flotillins specifically become localized in the uropod, both in immature and mature hematopoietic cells.
While membrane interactions are important for these peptides [44], confocal microscopy data obtained for the Combi peptide and several analogs show that they can rapidly become localized in the cytoplasm of bacterial cells, which suggests that they act on intracellular targets and that they are not strongly membrane-active [9], [45].
We found that wild type and SP domain mutated Gro/TLE1 proteins were all able to become localized in vivo to the promoter of the Ascl1/Mash1 (Ascl1) gene, a previously characterized [26] bona fide target of Hes1: Gro/TLE complexes (Figure S2).
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The subnet-based deployment makes the model more energy efficient as the problem becomes localized in a subnet.
Strain in this case becomes localized in a single plane of atoms that slips past its neighbors.
During germ cell specification in Drosophila, maternal nanos mRNA becomes localized in the germ plasm in the posterior part of the egg [12], [13].
Such organellar genes that became localized in the nucleus are translated in the cytosol and the proteins are targeted to the appropriate organelle [3].
It persisted in large particles but never became localized in its characteristic large crescent at the posterior tip of the oocyte (compare Figure 3A with Figure 3B).
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