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Under circumstances of falling malaria incidence, IPTi might become less efficacious and IPTc might be a good strategy to consider.
If resistance to oseltamivir increases, both prophylaxis strategies become less efficacious and less efficient, with more selection for resistance during continuous prophylaxis.
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In conclusion, the results presented here demonstrate that the same degree of β-secretase suppression (e.g., 50% by BACE1+/− deletion) becomes less efficacious and eventually ineffective in reducing Aβ/C99 accumulation and rescuing cholinergic neurodegeneration or memory deficits in 5XFAD mice as disease progresses into the more profound stage that is accompanied by BACE1 upregulation.
Surprisingly, (S -PA-824 becomeS -PA-824ficaciouS -PA-824ministered at 100 mg kg−1.
If resistance to oseltamivir was increased, both prophylaxis strategies became less efficacious and efficient, but postexposure prophylaxis posed a lower selection pressure for resistant virus strains.
Worryingly, these tools may become less effective.
Behavior might become less "average".
Courses would become less jammed.
We will become less intense.
Had the country become less recognizable?
Electronics have become less liable to explode.
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CEO of Professional Science Editing for Scientists @ prosciediting.com