Sentence examples for become inactivated from inspiring English sources

While the inactive X elect in female mutant embryos was decorated with Xist transcript and histone H3 trimethylated at lysine 27 (H3K27me3), many X-linked genes either failed to become inactivated or escaped X inactivation shortly after the initiation of silencing [ 31].

The high number of instances identified by ReKINect and detailed in Table S6 (427 unique kinase inactivation events) suggests that a large number of kinases become inactivated during cancer development.

The primary set of genes become inactivated, perhaps through mutation, leaving only the alternate pathway operating.

Another possibility is that the virus may have become inactivated in the mosquitoes or killed as the specimens were processed.

In addition, once NPs reach their midgut epithelial membrane, the enzymes become inactivated, and generate peroxide leading to cell death [36, 37].

Protein and enzyme are known to denature and become inactivated when they are exposed to biological surroundings such as temperature, mechanical forces, radiation, chemicals, and transition metals (Benjakul et al. 2011).

We have also observed that PD150606 becomes inactivated over time when dissolved in aqueous medium with an inactivation half life of 12 h.

First, during spermatogenesis the X chromosome of males becomes inactivated: since few testis genes are expressed post-meiotically, evidence suggests that chromosomal inactivation has promoted autosomal duplication events from X-linked genes [ 18, 29, 30].

Childs returned in 1953 to Johns Hopkins, and he eventually confirmed the Lyon hypothesis, in which one of the two X chromosomes in human female cells becomes inactivated randomly in order to accommodate expression of the single male X chromosome; prior to Childs's research, this process, known as "lyonization," had been observed only in female mice.

It could be explained that DNA lost its replication ability and the protein became inactivated due to the associating with the Ag+.

The inhibitory action of the microbes may be attributed to the loss of replication ability of DNA upon treatment with the silver ion, besides the fact that expression of ribosomal sub-unit proteins as well as some other cellular proteins and enzymes essential to ATP production becomes inactivated [27].