Therefore, our findings show that primitive myeloid cells are indeed the first blood lineages to become functional in the embryo, and they do so more than a day prior to the establishment of a functional vasculature.
NMDA receptors on motoneurons become functional in the prenatal period (Ziskind-Conhaim, 1990; Kalb & Hockfield, 1992), but they suffer a decline in function during the second postnatal week due to Mg2+ blockade (Arvanian et al., 2004).
Apps like Skype and WhatsApp will become functional in the country on Wednesday at midnight local time.
The HA requires proteolytic cleavage to become functional in membrane fusion.
In certain instances, in vitro differentiated hESCs can be integrated and become functional in transplantation experiments [3], [4].
In contrast, certain aspects of the BBB become functional in vivo before the appearance of astrocytes during development [ 93, 206].
Third, all small RNAs (sRNAs), such as microRNAs (miRNAs), small nuclear RNAs (snRNAs), tRNA-derived sRNAs (tsRNAs), small nucleolar RNAs (snoRNAs) and small interfering RNAs (siRNAs), are operational although they may be processed to become functional in different ways [10 12].
Additionally, the primary dermal barrier, which results from the deposition of lipids into the zona corneum, does not become functional in rats until the glucocorticoid surge just before birth (Aszterbaum et al. 1993).
Although only a subset of all tRNAs are encoded by intron-containing pre-tRNA sequences, each organism possesses at least one tRNA isoacceptor family of which all or almost all members depend on splicing in order to become functional in translation.
However, evidence of LGT from other bacterial endosymbionts has shown that the integrations of single genes or operons have become functional in host genomes, such as aphids (Nikoh et al. 2010), mealy bug (Husnik et al. 2013), and psyllids (Sloan et al. 2014).
