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"The supporters have tended to become fixed in a pattern of providing rather blanket defenses of the test instrument," he says.
Volkmann contracture, disorder of the wrist and hand in which the hand and fingers become fixed in a characteristic bent position.
The mathematical model showed that an introduced allele is more likely to become fixed in a population when that allele efficiently converts its corresponding allele into a match, and when the fitness costs to the individual are weak.
"The time for these CRISPR alleles to spread and become fixed in a population is on the order of tens of generations," said Rob Unckless, the paper's first author and a postdoctoral research fellow in the Department of Molecular Biology and Genetics.
So eventually, a given allele will eventually become fixed in a population, or go extinct, the latter being the more likely fate.
If selection would favor either one out of two mutations, but there is no extra advantage to having both, then the mutation that occurs the most frequently is the one that is most likely to become fixed in a population.
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If such a mutation were to become fixed in an certain portion of the population, which would then have reduced fertility with the rest of the population, the questions of one or more species within the human race would become very real, and lead to extremely serious ethical concerns.
Even if you don't put that little © on your work, you automatically get copyright protection the instant your work of expression becomes fixed in a tangible medium.
What factors determine the likelihood that a particular rearrangement becomes fixed in a population?
Neocentromere formation has been proposed to be the crucial first step in the seeding of an evolutionarily new centromere, which then becomes fixed in a species, resulting in a centromere repositioning event [ 28, 36].
Although it is now generally accepted that evolutionary breakpoints (i.e. rearrangement breakpoints that became fixed in a particular population) are not uniformly distributed on the human genome, the reasons why some regions tend to fix chromosomal rearrangements more than others still remains unclear and to date, no satisfactory explanation has yet been given at the whole genome level.
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