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The potent cytoprotective and folding properties of HSPs are co-opted during oncogenesis, as the HSPs become expressed at high levels to enable tumor cell growth and survival.
First, maternal transcripts for grna and grnb are readily detectable, with grnb showing higher abundance than grna until early somitogenesis when the two genes become expressed at similar levels.
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As a combination of these LETFs became expressed at substantial levels, hESC and rMAPC progeny should be poised to differentiate further towards mature hepatocytes, if supplied with additional proper cues.
After ablating SCD and OC from the meristem by pointing a laser beam at the meristem tip, WUS becomes expressed at the periphery, and the OC and SCD are regenerated with time [17], highlighting that cells at the periphery are capable of, but normally inhibited from the acquisition of OC identity.
For example, in pin7 embryos PIN4 becomes expressed at earlier stages of development and in the domain in which PIN7 is normally expressed, thereby compensating for loss of PIN7 function [ 84].
Most of the 33 pectin degradation genes remained repressed until the heart stage of embryo development in wild-type seeds and became expressed at the cotyledon stage of embryo development, concomitantly with endosperm degradation.
Lgr5 became expressed at earlier time-points, albeit at lower levels (both in terms of GFP fluorescence in the Lgr5+/EGFP-IRES-CreERT2 model and also mRNA levels analysed by qRT-PCR) compared to controls and when β-catenin signalling was increased.
If so the minor transcript could become expressed more highly at such time points.
The presence of these two marks in ESCs sometimes resolves to H3K4me3 in the more differentiated cell types at genes that become expressed (upper panel).
At the 40 43 somite stage, Hoxb13 and Hoxc13 become expressed in the tail-bud potentially terminating further ingression.
At a later stage, the immunoproteasome is expected to become expressed, which has a different specificity [46].
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