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This effect results from the density dependent growth of cancer stem cells; since this drug does not inhibit the stem cell population, resistant stem cells never become established due to the density constraint mechanism.
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The Eurasian tree sparrow has been introduced outside its native range, but has not always become established, possibly due to competition with the house sparrow.
Like yeasts, molds can become established in manufacturing factories due to poor process hygiene or spread from contaminated packages.
In a few short years, SBV has quickly become established in many countries in Europe, and due to increased international trade and travel, a new introduction of SBV into previously free countries cannot be ruled out.
Due to these difficulties, other techniques have become established as helpful in the searching process, which can involve either electronic or hand searching [ 25, 26]: – Reference or footnote tracking (looking back at studies referenced in articles found).
In addition, areas that are no longer suitable for one invasive species may quickly become established by a new invasive species as the old is less competitive due to decreased suitability of the habitat [8].
Moreover, pathogens that adapt to and become established in swine have a much higher probability of spreading to humans, due to the intensity of swine farming worldwide and the close contact between pigs and humans.
They were struck every year, except 1815 due to a shortage of metal, but were slow to become established in commerce.
For many years after its emergence, MRSA was associated with carriage or infection in the hospital setting where strains flourished due to the selection pressure of antibiotics but failed to become established in the community setting.
However, if plasmid-free segregants or cured derivatives die immediately (due to activity of these toxin antitoxin systems), they would never become established in the population.
DNA amplification (PCR) based tests are attractive due to their low cost and high speed and have become established as a mainstream diagnostic methodology for a variety of pathogenic organisms [ 29].
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