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Surprisingly, CD8 T cells become essential only after three weeks.
Thus, some genes become essential only under specific nutritional conditions, while others may become essential when one or more nonessential genes are knocked out.
Proline, glycine, serine and tyrosine are 'conditionally essential' amino acids, meaning they become essential only when the organism faces periods of extreme stress where the physiological need exceeds the organism's ability to produce.
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The mitochondrial ADP/ATP exhange acitivity is not essential for cell growth under fermentation culture conditions and becomes essential only under non-fermentation conditions.
A facultative role is also apparent in the mouse blastocyst where the Lif/Stat3 pathway becomes essential only during the extended maintenance of epiblast in diapause (Nichols et al., 2001).
They said securing an extension beyond 29 March had become essential with only days to go, although they warned that it also needed to be "long enough for a deal to be agreed".
Women, blacks and the poor have not only become essential parts of the public school system but have made great strides.
MTV, with its high-profile movie awards and endlessly repeated promotional documentaries on the making of one blockbuster or another, and its sister channel VH1 have become essential marketing tools not only for CD's but for movies and soundtracks.
Indeed, the book has become essential to western business leaders, not only if they want to – as they must – understand their new Chinese masters, but also if they want to get ahead in their chosen field.
Of the various ferroalloy metals that have become essential for industrial and military purposes, only molybdenum is abundantly available, while chromium, manganese, vanadium, tungsten, titanium, and cobalt are imported and stockpiledDomestic reserves of barites and uranium may be adequate, but the continent is deficient in tin, platinum, and bauxite (the principal ore of aluminum).
But will they ever really become essential?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com