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Mr Enever believes the character of crowdfunding has subtly changed and it has become difficult for small projects like his to get a look in.
It has become difficult for small and medium-sized private businesses (SMBs) -- the driving force behind China's manufacturing industry -- to access credit.
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Mauve has been widely used to analyze rearrangements and horizontal gene transfers that have occurred as microbial genomes have evolved [ 9], but visualization of relationships becomes difficult for more than a small number of genomes because hundreds of translocations and inversions are often seen even between genomes of closely related species [ 10].
Life soon became difficult for the signatories.
The lessons petered out [when] things became difficult for Julius".
It became difficult for biotechnology companies to go public.
Sensitive topics often became difficult for various individuals.
Some entrepreneurs say it's got so competitive, and there are now so many projects listed screaming for attention, that it has become very difficult for small players to get noticed.
While backing for the project locally has been strong, with hundreds of people making small investments to raise the money needed, and many volunteering their time and expertise to assist, the wider policy and regulatory environment has become increasingly difficult for small community energy schemes.
But as it becomes more difficult for small growers to turn a profit, they may go out of business, possibly leaving kush fiends with fewer options.
A consequence of the constant search of new partners by dominant pharmaceutical companies is that it becomes extremely difficult for small companies to maintain themselves for an extended time in an industrial network.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com