Sentence examples for become deleterious from inspiring English sources
Interestingly, surgery did not become deleterious, whereas medical management improved.
However, during septic shock, immunothrombosis may also become deleterious, contributing to major tissue insult and excessive coagulation activation [11 13].
On the other hand, thrombin can become deleterious if ongoing activation of the coagulation, owing to defective natural anticoagulants, leads to excessive thrombin formation.
Further studies need to confirm these data and to evaluate more precisely at which time point of the growth period and from which amount a localized peripheral growth plate injury may become deleterious for further longitudinal growth.
The concept of a Darwinian-evolutionary basis for the development of age-related diseases in principle postulates that genetic traits that are beneficial in younger years to allow for successful reproduction may become deleterious in the elderly, i.e. when selective pressure does not seem to be effective anymore.
Heat Shock Protein (Hsp) expression is increased when environmental conditions become deleterious including heat, hypoxia, heavy metals, oxygen radicals, radiation or osmotic changes [13].
Here, we analyze the phenotype of RhoE null mice and show that RhoE is essential for a correct development since the absence of RhoE expression induces severe behavioral and structural alterations and becomes deleterious few weeks after birth.
However, after Cit+ was refined by further mutations, this potentiating gltA mutation became deleterious to fitness.
Despite some convincing experimental data, no clinical trial has established the level at which pH becomes deleterious for hemodynamics.
Under subsaturating conditions, however, the R1039A mutant became deleterious, revealing a role of R1039 in substrate binding.
Once cells became strong citrate utilizers, the initial gltA mutation became deleterious driving the evolution of a diversity of secondary mutations to compensate for its cost.
