While the singer eschewed illegal narcotics, he became comprehensively addicted to painkillers such as Demerol, codeine, Percodan, Dilaudid, as well as a variety of stimulants and sedatives including Quaaludes.
With the development of high throughput methodologies such as ChIP-chip (reviewed in [17]) and more recently ChIP-seq (e.g. [18], [19]), it has become possible to comprehensively map regions in the genome of mammalian cells that are occupied by TFs of interest.
It becomes possible to comprehensively analyse cancers through a serum miRNA-based biomarker without the need for biopsy, surgery or other invasive methods.
With the availability of all these pathway-level aggregation methods, it becomes important to comprehensively evaluate how these methods compare with one another.
By using XCMS, we comprehensively identified metabolites that become isotopically enriched in HeLa cells after 48 h of U C glucose incubation.
With the development of high-throughput genomic technologies, it has become easy and cost-effective to comprehensively characterize clinical samples by a wide range of genomic data, e.g., depicting cancer samples from epigenomic, genomic and transcriptomic perspectives.
Microarrays have become an invaluable tool in toxicogenomics for comprehensively characterizing gene expression responses following treatment with an environmental contaminant, commercial chemical, natural product or drug as well as for investigating complex mixtures relevant to human and wildlife exposures.
As many of the previous barriers to HCV treatment have been comprehensively addressed, cost of treatment will become one of the most significant.
Finally, it will become far more difficult for the West to engage comprehensively with a Russian government that increasingly resembles a sultanate based on a personality cult.
Chancellor Angela Merkel's government has become the latest in Europe to insure private deposits comprehensively.
