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These observations support that pMN-like ERGs are selectively sensitive to the serotonin signal but only become competent to react to it after a lesion.
Of note, adding serotonin in the absence of a lesion is insufficient to induce proliferation or motor neuron generation, indicating that progenitors have to be in a lesion-induced sensitized state to become competent to react to serotonin.
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Alternatively, a repressor might have to be eliminated for a target gene to become competent to respond.
"If I ever become competent to read anything off the Internet..
Adequate knowledge and skills was required in order to become competent to provide support supervision.
However, little is known about how homologous chromosomes recognize each other and become competent to pair.
Signalling from the dense dermis induces rows of overlying epidermal cells to become competent to form the feather primordia.
During several days of starvation, a plasmodium grown to macroscopic size becomes competent to sporulate.
During development in all fruits, there is a period when the fruit becomes competent to ripen.
In turn, epithelial cells signal back to the stroma, which then becomes competent to support epithelial proliferation and differentiation [ 37].
Therefore, only cells in the outer layers of the meristem are competent to react to WUS-signal and we restricted stemness to the outer layers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com