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Nuclei that had been out of reach for experimental studies have now become available for study through a variety of approaches, both with in-beam spectroscopic methods and through spectroscopy following the decay of isomeric states or alpha decays at the focal plane of powerful separators.
Other features which have been selected less often by our algorithm, such as motifs 'GUGG'GCCGCC' and 'UCCG', might also be found to be of more importance when larger datasets become available for study in the near future.
In addition, an understanding of the effects of mutations in the neoadjuvant setting sets the scene (produces data useful for a power calculation) for trials that partner endocrine agents with new signal transduction agents, as and when these agents become available for study in the early disease setting.
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With the advent of the new X-ray missions Chandra and XMM-Newton, high-resolution spectroscopy has become available for studies of stellar coronae.
Once such abstraction has been adopted, a large number of graph-theoretical concepts and measures become available for studying and quantifying the topology of the graph.
A synchrotron X-ray fluorescence microprobe (SXRFM) has been in use at the National Synchrotron Light Source (NSLS), Brookhaven National Laboratory, since March 1986.[1] New higher flux third generation synchrotron X-ray sources such as the Advanced Photon Source (APS), Argonne National Laboratory, and several others have more recently become available for SXRFM studies.
South American frozen mummies from mountain tops of the high Andes have only recently become available for bioarcheological studies.
It may be that with the introduction of regular appraisal and audit in the UK such data may become available for future studies.
Public electronic repositories for these large-scale datasets, together with standards and open access publications for their description, have been important developments in the past decade for ensuring that they become available for further studies.
A second important development that will help to compare the specificity and sensitivity of ACPA (and other) tests is the initiative of the European AutoCure consortium to generate a large depository of sera from patients with RA and other rheumatic diseases that will become available for comparative diagnostic studies.
Data from the PROFILES registry will become available for noncommercial scientific research, subject to study question, privacy and confidentiality restrictions, and registration (www.profilesregistry.nl).nl
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