Since incubation of plasma with apoptotic cells induces nucleosome release via the serine protease activity of FSAP we argued that FSAP must become activated by interaction with those apoptotic cells [ 10].
Signal transducers and activators of transcription (STAT) proteins are latent transcription factors that become activated by phosphorylation on a specific tyrosine residue by JAK-family kinases (Darnell, 1997).
Signal transducers and activators of transcription (STAT) proteins are latent transcription factors that become activated by phosphorylation on a single tyrosine (near the carboxy-terminal of the molecule), typically in response to extracellular ligands [ 1, 2].
Signal transducers and activators of transcription (STAT), a family of latent cytoplasmic TFs which become activated by phosphorylation on a single tyrosine, can convey extracellular signals from kinds of cytokines, growth factors, or peptides to the nucleus [ 7].
Helper T cells become activated by interacting with antigen-presenting cells, such as macrophages.
Our smart LCM is made out of shape memory polymers that become activated by formation's natural heat.
This includes new materials that are imaging probes, which selectively accumulate in tumors, or that become activated by tumor-specific molecules in animal experimentation [15].
The central mediators of apoptosis include a group of cysteine proteases named caspases, which become activated by a proteolytic processing cascade in response to pro-apoptotic signals.
Thus, ILCs become activated by sensing danger signals from the tissue milieu rather than by antigen presentation with antigen-presenting cells (APCs) (Drake and Kita, 2014; Eberl et al., 2015).
The hierarchy of repeat-unfolding within fibrils is controlled not only by their relative mechanical stabilities, as found for single molecules, but also by the strength of cryptic interactions between adjacent molecules that become activated by stretching.
Among innate immune cells that reside in the brain, microglia sense danger signals represented by proteins like oAβ and become activated by neuronal damage such as that caused by bacterial endotoxins.
