Sentence examples for become a substrate for from inspiring English sources
Any RNA, when in a complex with another oligoribonucleotide known as an external guide sequence (EGS), can become a substrate for ribonuclease P. Simulation of evolution in vitro was used to select EGSs that bind tightly to a target substrate messenger RNA and that increase the efficiency of cleavage of the target by human ribonuclease P to a level equal to that achieved with natural substrates.
Rapid deposition of fibrin ogen) is observed in FeCl3-induced damage of mesenteric venules [39], allowing deposited fibrin ogen) to become a substrate for subsequent platelet recruitment, adhesion, and aggregation.
Such misfolded RNA may become a substrate for nucleases, thereby rendering it unstable.
However, H2O2 could become a substrate for cell wall peroxidases which are not inhibited when ascorbate levels are reduced [ 58].
In addition, the dismutation of superoxide radicals releases molecular oxygen that may become a substrate for the Aβ-dependent production of H2O2 (Fig. 8).
The findings described thus far indicate that MPP+ needs to be formed extracellularly to become a substrate for DAT and thus induce neurotoxicity.
However, this approach requires doubly transfected cells, whereby β-gal (lacZ expression) releases luciferin, which becomes a substrate for luciferase.
The truncated receptor then becomes a substrate for Psn, which processes it further to release the intracellular domain (ICD) from the membrane.
When this substrate was fully methylated by Dam, it became a substrate for the restriction enzyme DpnI, resulting in separation of fluorophore (fluorescein) and quencher (dabcyl) and therefore an increase in fluorescence.
Metalloproteases can proteolize the extracellular domain of a number of transmembrane proteins resulting in shedding of the soluble extracellular domain and the generation of membrane-bound CTF, which subsequently becomes a substrate for the PS/γ-secretase complex [35].
We submit that this latter result is direct evidence that cadherin-bound β-catenin, originating from dissociating AJ, travels to a site, the ERC, where it becomes a substrate for Wnt signaling.
