Sentence examples for become a substantial problem from inspiring English sources

"It could become a substantial problem," he said.

Currently, the availability of lowest-priced generic drugs in China has become a substantial problem [ 24].

Different sensitivities of Doppler signal acquisition have been shown to have a great influence on US assessments, resulting in only moderate intermachine agreement [ 30, 31], which might become a substantial problem for multicenter studies.

The worldwide increase in obesity and decrease in fertility suggest that incidence of endometrial cancer will continue to rise [ 4], indicating that endometrial cancer will become a substantial public health problem in the future.

Medical outliers have become a significant problem.

With the ageing population, this has become a substantial health and socio-economic problem for the developed world.

The emergence and spread of glycopeptide resistance in enterococci has become a substantial clinical and epidemiological concern, and vancomycin-resistant enterococci (VRE) are now an increasingly important problem in hospitals worldwide [ 1].

Indeed, accessories have become a substantial business for her company.

It could become a substantial development asset if managed properly, Stiglitz said.

"Downloads will become a substantial moneymaker for us," Mr. House said.

If they pull this off, this could become a substantial ad network.