The data sets acquired by the three different methods can principally be considered independent, because we used data collected using different detectors, and we did not select identical cell regions to extract donor/acceptor signal or emission spectra data for any of the quantitative methods.
Our results are generalizable to the wider Korean population because we used data from a large, nationally representative, longitudinal survey.
However, because we used data from <56 days before the index day, the stratified 28-day baseline will include only ≈16 days for weekend days.
Issues surrounding non-random sampling are also moot because we used data on neonatal mortality for the entire newborn population in Taiwan between 1998 and 2004.
Because we used data from the Social Insurance Office, no sick-listing data was missing, except the possible short-term relapses of non-return-to-work during the follow-up months.
Furthermore we do not have information on the reason for hospitalizations in the last month, because we used data recorded by existing GP networks, which did not contain information on this subject.
51 52 Because we used data only from verified potential cases we could have missed false negative cases in the remainder of the cohort as type 2 diabetes can remain undiagnosed for several months to years.
The mutation in the DMRT3 gene was not genotyped directly for any of the horses because we used data from a previous genotyping study without the possibility to re-use blood samples or to genotype other horses.
The cost effectiveness of the new oral anticoagulants might be overestimated in this study, because we used data from the three large randomized trials, which might not represent the real-world population.
Because we used data from an intervention study including diet, physical activity, and cessation of smoking, this might be a confounder in the association between sleep and type 2 diabetes, but we believe the impact must be small because adjustment for intervention did not influence the results.
