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Because we previously identified an interaction between the QTL on each of the three major autosomes as necessary for complete sterility [20], [23], females from mapping lines were then crossed to males heterozygous for the chromosome-3 and either the chromosome-4 or the chromosome-2 QTL.
Because we previously identified InsP3R as the primary Ca2+ channel involved in Ca2+ transfer to the mitochondria, we evaluated the subcellular distribution of the most expressed InsP3R type 2 isoform (InsP3R2) and the mitochondrial marker mtHsp70.
Because we previously identified the estrogen-related receptor (ERR γ) as the main activating factor for the strong induction of PDK4 by matrix detachment, we tested if induction of MnSOD was also dependent on ERR γ.
The results from one of the identified publications are not included in the systematic review because we previously identified and used another manuscript that presented results on the same patient population.
Because we previously identified a theta/alpha (7 12 Hz) phase synchrony difference between successful and unsuccessful encoding early in the post-stimulus period, we also calculated the correlation between phase alignment of these oscillations and subsequent CFC.
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In the combined NHS-NHSII nested case-control study dataset, we assessed for interactions between the presence of each polymorphism and cigarette smoking categorized both as ever/never, and then dichotomized as ≤10 or ≥10 pack-years of smoking, because this is the threshold we previously identified to be associated with increased risk for RA [ 35].
We used the level with 29 clusters spanning the conterminous U.S. because that was one level that we previously identified as optimal based on standard diagnostic metrics for hierarchical clusters (Costanza et al. 2017).
We focused on the mutSOD1/Bcl-2 interaction because in mutSOD1 ALS mice and patients, we previously identified this aberrant protein complex occurring in spinal cord but not liver mitochondria (7), a pattern that correlates with the tissue specificity of the disease.
We previously identified a native electron transport system for CYP175A1.
We previously identified several dysfibrinogenemias in some patients with CTEPH.
We previously identified several DISC1-interacting factors [14], [15], [16].
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