The analysis is not affected by the different rates of evolution because what we characterized is the clan AA protein domain based on all possible phylogenetic signal and not the functional families.
Although ABA92 and ABA109 were highly similar in their sequences, we characterized them separately, because even single-nucleotide differences have been shown to affect aptamer affinity and specificity.
The Monte Carlo uncertainty analysis described here can be considered a screening-level uncertainty analysis because we have characterized uncertainty in the environmental model estimated PWD PFOA concentrations as a surrogate for hundreds of parameters in the suite of fate and transport models used to estimate the PWD PFOA concentrations.
We characterize them as virtual because they are not to be accounted in the value n (the total number of real nodes) as defined in Assumption 3.
Mr. Bharara on Tuesday rejected such arguments, which he characterized as "because we're so big, to take action against us, the sky is going to fall".
These bacteria are a wide-spread model organism in modern toxicology because well characterized physiology and ease of genetic manipulation [ 24].
We chose this particular combination of cell lines because we have previously characterized the antigen-stimulated redistribution of intracellular proteins (including PKCθ) in the D10 line [ 6], and because D10 T cells and fibroblasts have very different sizes and morphologies, allowing us to confirm the identity of each cell type independently of fluorescence data.
Because we wanted to characterize the distributions of all labeled neurons across brains, we decided to use light sheet microscopy on cleared brains.
Two different species, H. salinarum and H. volcanii, were used for the analysis, because we aimed to characterize the evolutionary conservation of translational regulation.
We further characterized this protein because it was one of the major proteins of NH04 and reproducibly more abundant at 10°C.
