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The PRECIS instrument was developed because "very few trials are purely pragmatic or explanatory" but rather vary along a continuum within key domains [ 41].
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First, because many of the infants participated in very few trials, our data may not adequately represent a child's attentional bias or difficulty to disengage from a threat.
The only time you really hear both sides is when the case goes to trial, and there are very few trials these days".
Considering the presence of very few trials that can be included in the review, publication bias could not be assessed.
However, the problematic reviews identified in our study included very few trials and relatively few participants.
Trials typically were four weeks long, and very few trials were longer.
Very few trials in severe malaria have been powered to detect mortality differences.
While very few trials utilized single QoL instrument, others used multiple instruments for QoL measurement.
Very few trials have looked at predictive biomarkers that would allow better patient selection.
Very few trials, however, have as yet directly addressed xenon neuroprotection.
However, they used only very few trials (i.e., a single decision in Experiment 3).
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