Sentence examples for because this pathway is from inspiring English sources

The latter mechanism seems more plausible because this pathway is enabled only when the high dose of FVIIa is provided and does not require the presence of factors V, VIII, and IX.

Because this pathway is stoichiometrically trivial, this allowed a direct comparison between all interactions in the pathway.

The involvement of the JNK pathway is of interest because this pathway is responsible for the proliferative signalling emanating from apoptotic cells (Pérez-Garijo et al., 2009).

The enzymes of the bacterial transsulfuration pathway, cystathionine γ-synthase and cystathionine β-lyase, are attractive targets for the development of novel antimicrobial compounds because this pathway is unique to plants and bacteria.

We focused on hexosamine biosynthetic pathway in astroglia (Matthews et al.. 2007), because this pathway is known to produce ER stress (Kline et al., 2006; Sage et al., 2010) under hyperglycaemic conditions (Özcan et al., 2004).

The ability of TN to inhibit MAPK signaling pathway could also explain its antimetastatic potential, because this pathway is known to be implicated during the epithelial to mesenchymal transition (EMT), which is important for tumor cell invasion [ 57].

Inhibitors of PI3K hold promise for the treatment of breast cancer because activation of this pathway is highly prevalent.

Similarly, glucocorticoid receptor activation, another metabolic nuclear receptor recently proposed for integration in EDC testing frameworks (OECD 2012a), may be a valuable single end point screen because stimulation of this pathway is known to induce IR (Qi and Rodrigues 2007).

Because deregulation of this pathway is linked to developmental skeletal deformities and the mechanism is conserved in both zebrafish and mammals (Laue et al. 2011), a pathway-based NOEL of 1.35 µM and a lowest observable effect level of 2.8 µM flusilazole could be reasonably derived from the point at which the retinol metabolism pathway significantly departed from the control.

The dramatic induction of these two enzymes could result from the P-type plantsufferingng more serious damage under insect infestation and because the regulator of this pathway is still functioning.

The remaining orphan activity present in the Lipid IVA pathway was also removed from the model because it is assumed that this pathway is not present in the metabolism of B. cuenoti.