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Because this duplication contains 4 genes it is not immediately clear which gene is responsible for the observed behavioral differences.
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This analysis showed that all duplication containing haplotypes are associated with higher anxiety-like behavior, which is consistent with a direct role for the duplication in behavior.
Because the telomeric limit of the duplication contained greater than 95% repetitive sequence, we designed probes to span the centromeric limit.
This is consistent with duplication in tandem spanning the full length of the HPR gene, corresponding to the annotated segmental duplication containing the HPR gene.
The mouse promoter does not contain this duplication, and initiates in a single peak that is weakly aligned to the human, but contains the same EWS motif.
So if you were using two gigs of space on Gmail you could easily be using six at FastMail because of this duplication.
Cutler et al [16] suggested that many CNVs, including the duplication of Glp1r, which is contained in this duplication, might be responsible for differences in food intake among inbred strains.
It is interesting to note that ALDH2 (encoding the aldehyde dehydrogenase 2 enzyme) is fully contained within this duplication.
This method contains four steps projection, duplication, description, and calibration and it is incorporated in a novel software tool.
However, this ThyX contains a domain duplication.
This work described a repeated gene duplication cassette containing a miRNA and four repeats that resemble a miRNA cluster on Chr19.
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