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"People were claiming that they had [stem cell-derived] neurons, because they were expressing beta-3 tubulin which is one of the markers of neurons, but when I looked at them they were like fibroblasts, not really differentiating with axons, neurites, and synapses," says Stoppini.
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Among the genes with over-dominance mode, TabZIP26, TabZIP37, TabZIP86, TabZIP94 and TabZIP134 showed similar expression trend because they were expressed maximally in the F1 and had the lowest expression level in TY806.
Concurrently, Palin's denunciations of the Obama White House via Twitter garnered substantial attention not because the opinions were especially novel but because they were expressed with the brashness of a wily headline-grabber.
Also, genes were selected because they were expressed in taste buds and not significantly expressed in adjacent LE.
Preliminary edits resulted in 6,077 probes being discarded because they were expressed at levels below the sensitivity of the platform (i.e., negative signal to noise ratio) in all hybridizations.
We focused on the Group A genes because they were expressed earlier and thus more likely to include stimuli for Phase I and II (Fig 1C).
These CLDN genes were chosen because they were expressed at detectable levels in several tissues and represented a wide variety of different expression patterns as suggested by the SAGE database analysis.
This exclusion was particularly important when comparing to CLIP results; CLIP can only evaluate mRNAs expressed in the cells, which would impart a trivial relative advantage if the computational predictions included targets that appeared unresponsive because they were expressed below the array background.
Neither AMOTL1 nor AMOTL2 was quite as effective as AMOT p130 in rescuing HIV-1 infectivity in this assay, possibly because these proteins are intrinsically less active than AMOT p130 and/or because they were expressed at lower levels (left panel 2, compare lanes 3 5).
The majority (59.9%) of these genes were not identified by SAGE because they were expressed at too low of a level; either no SAGE tags were detected (24.5%), or the germline SAGE tag count was below our threshold (≤ 9) and not counted in our analysis (35.4%).
Trump and Sanders are popular not just because they're expressing people's anger but because they offer timely critiques of American capitalism.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com