These factors were selected on the basis of evidence of their association with the risk of delirium and because they were amenable to intervention.
As well as completing the measures (described below and chosen because they were amenable to short-term change) participants were asked to feedback in free text on the process of the mentoring scheme itself (e.g. registration, matching, training, how many meetings they had had, what was discussed and any perceived benefits or gains of mentoring).
The small animal models are currently popular because they are amenable to genetic engineering and are relatively inexpensive.
We further investigated the role of PARD6B and PARD6G in regulation of the Akt pathway using 2D cultures of MCF10A cells, because they are amenable for biochemical analysis.
Genetic explanations, on such a view, are pragmatic: there is a practical context in which genes are singled out as causes not only because they are amenable to technological control but because they are increasingly perceived to be more tractable than their nongenetic counterparts and therefore the best means to a variety of ends (Gannett 1999).
HCT116 cells were chosen because they are amenable to homologous gene recombination and p300 has been found to be mutated in many colorectal cancers.
Nanosecond gycosidic-linkage dynamics are better understood because they are amenable to study by both nuclear magnetic resonance (NMR) spectroscopy and simulation.
As detailed below, in this article, we concentrate in this first instance on using the first of these three correlations to our advantage, partly because they are amenable to exact analysis to verify the results.
To address the importance of TPCs in TCR activation, we used Jurkat cells transduced with the NY-ESO-1157 165-HLA A2-restricted TCR 1G4 [ 25], hereafter referred to as Jurkat 1G4 cells, because they are ameNY-ESO-1157 165-HLAnipulation NY-ESO-1157 165-HLA TCR, which has the same specificity as the TCR expressed by the 4D8 CD8+ T cell cloNY-ESO-1157 165-HLA
Further, these cell lines serve as a platform for in vitro and in vivo interrogation because they are amenable to growth in subcutaneous space, in sites common for metastasis such as the liver, and in the native colonic environment of syngeneic, immunocompetent recipients (Martin et al., 2013).
Because they were technically more amenable than Drosophila S2 cells, human HEK293T cells were transiently co-transfected with the TnnT3 minigene and plasmids expressing all four Muscleblind protein isoforms fused to GFP.
