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Exact(1)
The classic colchicine site agents (e.g. colchicines, combretastatins, podophyllotoxin), most of which are structurally similar and rather complex in nature, are not used in the clinic because they are systemically toxic.
Similar(59)
He suggested that the major banks required more supervision and regulatory time because they were so complicated and because they were systemically important.
They were systemically incompetent, which is actually far worse.
Given this toxicity, aminoglycoside treatment for bacterial infections is performed judiciously in developed countries, often being used topically or as the drug of last resort but they are used systemically in underdeveloped countries primarily because they are inexpensive [ 13].
Because they are growing.
Because they are entrenched.
Because they are sad.
"Because they are".
"Because they are there".
That's because they are.
Or because they are serfs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com