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The scientific community predominantly considers estrogens to be epigenetic carcinogens because these compounds do not induce mutations in standard bacterial and mammalian test systems.
Because these compounds do not interact with classical ERs, it is also likely that they will not trigger the unwanted side effects of chronic hormone therapy in postmenopausal women, such as increased risk of thrombosis, stroke, cardiovascular events and breast cancer, associated with the activation of classical ERs [3], [4].
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Because these compounds did not show maximum induction compared with E2, relative potency based on the EC20 would be more reliable than that derived from the EC50 (Villeneuve et al. 2000).
These compounds do not have breakpoints because they are new antibiotics (Table 1).
Thus, these compounds do not kill the cell by inhibiting the binding proteins, because cells lacking the proteins are still viable.
These compounds do this by preventing the breakdown of the neurotransmitter by an enzyme.
These compounds do not occur in nature.
The purchaser of these compounds does not get evaporated milk.
These compounds did not inhibit expression of myc or fos.
The compound pair ' glucose<=>ADP' cannot be defined as a reactant pair because these two compounds do not conserve any atoms in a reaction.
We skipped the encodings based on the PPP typer because several compounds do not have any pharmacophore point according to the PPP definition.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com