These miRNAs were excluded from further analyses, because their expression patterns were inversely different from those reflected in the array-based results.
The results showed that L75 and L90 were initially clustered together because their expression profiles were similar; E75 and E90 were clustered in another class.
These results indicate that in one miRNA family different members show clearly different expression levels, probably because their expression is tissue- or developmental-specific.
This result argues against FSHD-related differences in posttranscriptional processing of the products of these four genes in myoblasts because their expression is autoregulatory [ 49- 52].
Regulation of RPGs is important because their expression is regulated very precisely: each ribosome contains exactly one each of up to 84 different proteins, and errors in the expression levels of these genes will result in malformed ribosomes [ 1].
As a result, if Gγ2 and Gγ4 acted via these receptors in vivo, the wide distribution we observed could exist because their expression parallels that of their target GPCRs.
According to our results, we proposed that the key rate-limiting genes of FA synthesis may include ACP, KAS and FATA because their expression showed linear relationships with synthesis of FAs in H. pluvialis.
Because NOS2 expression resulted in Ets-1 (thr 38) phosphorylation, we also examined the effect of NO signaling on Ets-1 activation in human ER- breast cancer cell lines treated with NO releasing compounds.
We found that PthC1 elicit not only a different but also an opposite effect of PthA2 and PthA4, because its expression resulted in a general down regulation of genes involved in auxin and gibberellin synthesis and signaling, cell-wall remodeling, cell division, and defense responses (Additional file 3).
Redundancy in representation of genome sequences by the genomic library generated for microarray construction [ 26] is reflected in stage-specific gene expression results because some clones represent the same differentially regulated gene (Table 2).
