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These results may actually underestimate the abundance of NITEGE generated in the meniscus because the surface zones of this tissue (removed for the explant experiment) appear to have robust aggrecanase activity, consistent with previously reported elevation of MMP-3 expression, aggrecanase activity, and sGAG release from IL-1-treated surface-zone meniscal fibrocartilage from mature bovines [ 51].
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Another classification distinguishes the surface zones, or facies, on parts of a glacier.
The surface zone and the body of the lesion in experimental D1 and D2 groups were less homogenous because of the lower pore volume.
Specimens from Patient 3 contained fibrous cartilage in the deep zone and fibrous tissue in the surface zone (Fig. 5I).
Upregulation of TLRs was first seen in the surface zone and later in the middle zone, and even in the deep zone.
In normal cartilage, FN is localized mainly in the matrix of the surface zone.
This process is rapid, dynamic and begins at the surface zone of articular cartilage.
As shown, FCGR3B protein was detected in the surface zone of normal menisci.
In grade-1 OA samples, TLR1+ chondrocytes were confined to the surface zone.
The results of all measurements of the extent of the surface zone, the body of the lesion, and of the translucent zone are presented in Table 3.
— America's only Blue Zone — because, on the surface, it's unlike the world's four other longevity zones.
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