Sentence examples for because the primary endpoint from inspiring English sources

Nonetheless, frequent adaptation in oncology is hampered because the primary endpoint of greatest interest, OS, takes significant time to collect.

Second, because the primary endpoint is variceal rebleeding, the power calculation is primarily based on a difference in the rate of variceal rebleeding between both groups.

The 2.5% significance value is chosen to adjust for the multiple comparisons, because the primary endpoint will be tested on the patient and partner separately.

A surrogate primary endpoint, the number of dilatation sessions required, was subsequently included in the analysis because the primary endpoint did not reach statistical significance.

The risk of a clinically significant type 2 error is low because the primary endpoint was achieved in 12% of the acupuncture group compared with 14% in the control group, with a 95% CI of 0.33 2.2 for the relative risk.

HER2 positivity was not required because safety was the primary endpoint.

Consequently, the development of clinical trials with useful endpoints is challenging because mortality, as the primary endpoint, is usually not feasible.

Although a cohort study such as this one has many exposures, time points, and endpoints of interest, we chose to power our study using cardiorespiratory fitness at one-year follow-up as the primary exposure/time point, and recurrence free interval (RFI) as the primary endpoint because of the importance of these variables but also because of the substantial power needed to detect this association.

This number was extended to 114 because of missing data on the primary endpoint.

We chose the volume of secretion present at extubation as the primary endpoint because the device was primarily designed to remove secretions, either by aspiration or cleaning.

However, patients with TTH were less likely to reach the primary endpoint because of the high number of 27 headache days at baseline.